Press Releases in 2010

Novus Biologicals, a leading supplier of hypoxia-inducible factor (HIF) antibodies, launched a new mouse monoclonal HIF Prolyl Hydroxylase 3 antibody this week (catalog number NBP1-30440).  This antibody, clone EG188e/d5, is made to the partial recombinant human PHD3 protein (UniProt accession number Q9H6Z9).  It cross-reacts with bovine, human,  monkey, mouse and rat, and is useful for Western blot analysis and immunohistochemistry on paraffin-embedded sections.  NBP1-30440 was QC tested on Cobalt

The Novus Product Development Team is excited to announce the launch of a new antibody target not currently available by any other antibody supplier.

Novus Biologicals is proud to be involved with Capitol Hill Community Services (CHCS) by volunteering time to serve the Denver metro homeless community. Novus employees volunteer twice a year at Trinity United Methodist Church to help serve lunch to the disadvantaged.  Following lunch, the volunteer regimen also includes cleaning the lunch tables, stacking chairs, sweeping and mopping.

Novus Biologicals carries an extensive line of LOX and LOPP antibodies.   A recent addition to this group of antibodies is a new anti-LOX Propeptide antibody (catalog number NBP1-30327).  This rabbit polyclonal antibody was made to an internal region of the human protein within amino acid residues 118-168.  This antibody is unique and especially useful, as it recognizes the glycosylated propeptide form (~35 kDa), as well as the proenzyme form (~50 kDa).  NBP1-30327 was QC tested in Western blot on MDA-MB-231, a hu

Novus Biologicals, a leading supplier of hypoxia-inducible factor (HIF) antibodies, recently launched two new HIF related antibodies: an anti-Factor Inhibiting HIF-1 antibody (catalog number NBP1-30333) and an anti-HIF Prolyl Hydroxylase 2 antibody (catalog number N

Novus Biologicals just released a new anti-CLOCK antibody (catalog #: NBP1-30326).  The CLOCK protein, also known as KAT13D, belongs to the basic helix-loop-helix (bHLH) family of transcription factors.  It is a major protein of interest in the study of circadian rhythm as polymorphisms within the encoded protein have been shown to be associated with abnormal circadian rhythm behavior, such as sleep disorders.

Novus Biologicals recently launched new Hepatic Cell Marker antibodies and Pancreatic Cell Marker antibodies to compliment their current Stem Cell Marker product line.

Loading controls are important tools in Western blot analysis that help researchers to ensure that their samples were loaded equally across the gel.  When selecting a loading control, it is important to choose a protein that has a different molecular weight than the protein being studied; this ensures that distinct bands are achieved.  Novus Biologicals provides an extensive line of loading controls, including Actin,

This week Novus Biologicals unveiled their first poster on the mTOR pathway.   One of Novus’ major focuses of 2010 is the creation of pathway posters.  These posters provide researchers with a detailed visual of molecular pathways and also the products that Novus provides to targets within these pathways.   The mTOR poster is 18 x 24 inches in size and comes in a 4-fold format for ease of handling.

An epitope is the portion of a molecule to which an antibody binds. Epitope tags are artificial epitopes, also known as antigenic determinants, which are engineered using recombinant DNA technology into a protein sequence by placing the sequence encoding the epitope within the same open reading frame of the protein encoded by the gene sequence. Epitope tags are generally composed of amino acids ranging from 10-15 in length and are usually engineered onto either the N- or C- terminus in order to minimize tertiary structure disruptions that may alter protein function.