Novus Biologicals releases new stem cell marker antibodies

Novus Biologicals recently launched new Hepatic Cell Marker antibodies and Pancreatic Cell Marker antibodies to compliment their current Stem Cell Marker product line.

The study of progenitor activation in the liver is of significant interest to the bioscience community, however reagents for the study of distinct hepatic subpopulations are very limited.  Novus Biologicals recently released a new line of nine surface reactive monoclonal antibodies specifically for the study of the murine oval cell response.  Oval cells are hepatic stem cells that are thought to be bipotential progenitors capable of yielding both hepatocytes and bile ducts. Each of these antibodies recognize a surface antigen present on a liver cell subset and allow researchers to isolate the subpopulation via FACS.  (Dorrell C, et al. 2008. PMID 18726953).  These nine new anti-Oval Cell Marker antibodies include:

 

  • Oval Cell Marker Antibody (MIC1-1C3) - hepatic duct cell marker (NBP1-18961)
  • Oval Cell Marker Antibody (OC2-2F3) - hepatic duct cell marker (NBP1-18964)
  • Oval Cell Marker Antibody (OC2-1D11) - hepatic duct cell marker (NBP1-18963)
  • Oval Cell Marker Antibody (OC2-6E10) - hepatic periductal cell marker (NBP1-18981)
  • Oval Cell Marker Antibody (OC2-4E8) - hepatic periductal cell marker (NBP1-18971)
  • Oval Cell Marker Antibody (OC2-1C6) - hepatic periductal cell marker (NBP1-18965)
  • Oval Cell Marker Antibody (OC2-3C7) - hepatic periductal cell marker (NBP1-18970)
  • Oval Cell Marker Antibody (OC2-3C5) - hepatic periductal cell marker (NBP1-18968)
  • Oval Cell Marker Antibody (OC2-2A6) - hepatic periductal cell marker (NBP1-18967)

Novus Biologicals also launched a line of ten new pancreatic cell marker antibodies that are useful for targeting cell surface molecules on developing and mature pancreatic cells. These antibodies were  identified by specific binding of surface antigens on islet (panendocrine or alpha-specific) and nonislet pancreatic cell subsets (exocrine and duct). These antibodies were used to isolate populations of alpha, beta, exocrine, or duct cells from primary human pancreas by FACS and to characterize the detailed cell composition of human islet preparations (Dorrell C, et al. 2008. PMID 19383399).  These ten new pancreatic cell marker antibodies include:

 

  • HPa1 Antibody (DHIC2-2C12) - Alpha cell marker (NBP1-18949)
  • HPa2 Antibody (DHIC2-2B4) - Alpha cell marker (NBP1-18950)
  • HPi1 Antibody (HIC0-4F9) - Endocrine pan-islet cell marker (NBP1-18872)
  • HPi2 Antibody (HIC1-2B4.2B) - Endocrine pan-islet cell marker (NBP1-18946)
  • HPi3 Antibody (HIC1-7H10) - Endocrine pan-islet cell marker (NBP1-18947)
  • HPi4 Antibody (HIC1-5F10) - Endocrine pan-islet cell marker (NBP1-18948)
  • HPx1 Antibody (HIC0-3B3) - Exocrine cell marker (NBP1-18951)
  • HPx2 Antibody (HIC0-1C10) - Exocrine cell marker (NBP1-18952)
  • HPd1  Antibody (DHIC2-4A10) - Pancreatic and liver duct cell marker (NBP1-18953)
  • HPd2 Antibody (DHIC2-5H10) - Pancreatic and liver duct cell marker (NBP1-18955)

In addition to these new Hepatic Cell Marker antibodies and Pancreatic Cell Marker antibodies, Novus Biologicals also provides a wide range of other Stem Cell Marker research tools.

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For more information on Novus Biologicals' stem cell product line or to inquire about product collaborations, please contact the Novus Product Development Team by calling 303-730-1950 or via e-mail at collaborations@novusbio.com.

Release Date: 
Thursday, February 18, 2010 - 07:00