LIGHT/TNFSF14 Products

Description

TNFSF14 is encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.

Bioinformatics

Entrez	8740 Human
Uniprot	AAC39563 Human NP_003798 Human NP_003798.2 Human O43557 Human
Product By Gene ID	8740
Alternate Names	CD258 antigen CD258 delta transmembrane LIGHT Herpes virus entry mediator ligand Herpesvirus entry mediator ligand HVEM-L HVEMLherpesvirus entry mediator-ligand ligand for herpesvirus entry mediator LIGHTherpesvirus entry mediator A LTg TR2 tumor necrosis factor (ligand) superfamily, member 14 tumor necrosis factor ligand superfamily member 14 tumor necrosis factor receptor-like 2 tumor necrosis factor superfamily member LIGHT

Research Areas for LIGHT/TNFSF14

Find related products by research area and learn more about each of the different research areas below.

Apoptosis