RASSF1 Products

Description

The tumor suppressor gene RASSF1A (3p21.3), human Ras association domain family 1A, is expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, small intestine, colon, and peripheral blood leukocytes. RASSF1A expression is inhibited by hypermethylation of the CpG island including the promoter and early transcribed regions of the human RASSF1A gene. Hypermethylated RASSF1A promoter is observed in primary tumors. Furthermore, RASSF1A is related with cell cycle regulation, apoptosis and microtubule stability. Agathanggelou A. et al

Bioinformatics

Entrez	11186 Human 28844 Human
Uniprot	NM_007182 Human NP_009113 Human NP_009113.3 Human NP_733830 Human Q9NS23 Human
Product By Gene ID	11186
Alternate Names	123F2 NORE2A pancreas-specific ras association domain family 1 protein Ras association (RalGDS/AF-6) domain family member 1 ras association domain-containing protein 1 RASSF1A RDA32cardiac-specific ras association domain family 1 protein REH3P21 tumor suppressor protein RDA32 WUGSC:H_LUCA12.5

Research Areas for RASSF1

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cell Cycle and Replication
Mitotic Regulators

Related RASSF1 Blog Posts

Check out the latest blog posts on RASSF1.

The role of DNMT3B in the co-incidence of methyltransferase and tumor suppressor expression in malignancies Epigenetics is the process of heritable change in gene activity despite alteration of the hosts DNA sequence, essentially causing a change in a phenotype without a change in the genotype of a host. To change the gene sequence without interfering w...    Read more.

Role of RASSF1A in Death Receptor-Dependent Apoptosis Death-receptor apoptosis, or cell death, is essential for cellular growth regulation; its disruption is expressed in a variety of cancers. We at Novus Biologicals are one of the leading antibody suppliersfor apoptosis and cancer research groups, and t...    Read more.

Read more RASSF1 related blogs.