VIPR2/VPAC2 Antibody

Immunohistochemistry-Paraffin: VIP R2/VPAC2 Antibody [NLS1305] - Anti-VPAC2 / VIPR2 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: VIP R2/VPAC2 Antibody [NLS1305] - Analysis of anti-VIPR2 antibody with human liver and bile ducts.

Immunohistochemistry-Paraffin: VIP R2/VPAC2 Antibody [NLS1305] - Anti-VPAC2 / VIPR2 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: VIP R2/VPAC2 Antibody [NLS1305] - Anti-VPAC2 / VIPR2 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Product Discontinued

VIPR2/VPAC2 Antibody Summary

• Immunogen: Synthetic 16 amino acid peptide from C-terminus of human VIPR2.
• Specificity: Human VIPR2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Monkey (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: VIPR2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 3 ug/ml-23 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (94%), Marmoset (88%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for VIPR2/VPAC2 Antibody

• FLJ16511
• Helodermin-preferring VIP receptor
• PACAP type III receptor
• PACAPR3
• PACAP-R3
• PACAP-R-3
• Pituitary adenylate cyclase-activating polypeptide type III receptor
• vasoactive intestinal peptide receptor 2
• vasoactive intestinal polypeptide receptor 2
• VIP R2
• VIP2R
• VIPR2
• VIP-R-2
• VPAC2
• VPCAP2R

Background

Vasoactive intestinal polypeptide receptor 2 (VIPR2) is a member of the Vasoactive Intestinal Polypeptide subfamily. It is characterized by a high affinity for the VIP analogue from lizard venom named helodermin, a preference for the neuropeptide PACAP-38 over PACAP-27 and VIP, and an extremely low affinity for secretin. VIPR2 has been suggested to affect the rhythmicity and photic entrainment of the circadian clock. VIPR2 expression has been reported in a wide variety of tisseus. ESTs have been isolated from heart/melanocyte/uterus, liver/spleen, and prostate libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for VIPR2/VPAC2 Antibody (NLS1305)(1)

Publication using NLS1305

• Berger EA, Vistisen KS, Barrett RP, Hazlett LD. Effects of VIP on corneal reconstitution and homeostasis following Pseudomonas aeruginosa induced keratitis Invest Ophthalmol Vis Sci 2012-10-04 [PMID: 23036997]

FAQs for VIPR2/VPAC2 Antibody (NLS1305). (Showing 1 - 1 of 1 FAQ).

1. What is the peptide sequence of the immunogen for this product?
   • The specific immunogen for this item is proprietary, however, I can provide you with the amino acid range for this antibody.The immunogen falls between aa 381-410. The sequence is from the human VIPR2 protein Uniprot site.

Bioinformatics

• Gene Symbol: VIPR2
• Entrez:
  • 7434(Human)
• Uniprot:
  • P41587()