VIPR2/VPAC2 Antibody (476031) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: IHC
• Clone: 476031
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

VIPR2/VPAC2 Antibody (476031) [Alexa Fluor® 488] Summary

• Immunogen: NS0 mouse myeloma cell line transfected with human VIP R2
  Glu24-Ile438
  Accession # P41587
• Specificity: Detects human VIP R2 in direct ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for VIPR2/VPAC2 Antibody (476031) [Alexa Fluor® 488]

• FLJ16511
• Helodermin-preferring VIP receptor
• PACAP type III receptor
• PACAPR3
• PACAP-R3
• PACAP-R-3
• Pituitary adenylate cyclase-activating polypeptide type III receptor
• vasoactive intestinal peptide receptor 2
• vasoactive intestinal polypeptide receptor 2
• VIP R2
• VIP2R
• VIPR2
• VIP-R-2
• VPAC2
• VPCAP2R

Background

Human VIP R2 (Vasoactive intestinal polypeptide receptor 2) is a 47 kDa (predicted) seven transmembrane receptor that belongs to the G protein coupled receptor 2 family of proteins. In addition to the seven transmembrane regions, the mature chain also contains in its first extracellular region a hormone receptor domain (aa 49‑114), which includes three N-linked glycosylation sites. Human VIP R2 shares 85% aa identity with mouse and rat VIP R2. VIP R2 is expressed predominantly in skeletal muscle and to a lesser extent in the brain, heart, pancreas, and placenta. VIP R2 is coupled to a cAMP mediated signal transduction pathway and binds VIP and pituitary adenylate cyclase activating polypeptide (PACAP).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.