Urotensin-II R/GPR14 Antibody (443707) [Alexa Fluor® 488]

• Reactivity: Mu
• Applications: Flow
• Clone: 443707
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 488

Urotensin-II R/GPR14 Antibody (443707) [Alexa Fluor® 488] Summary

• Immunogen: Mouse Urotensin-II R synthetic peptide
• Specificity: Detects mouse Urotensin-II R. Stains mouse Urotensin-II R transfectants but not irrelevant transfectants in flow cytometry.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 0.25-1 ug/10^6 cells

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Urotensin-II R/GPR14 Antibody (443707) [Alexa Fluor® 488]

• G protein-coupled receptor 14
• GPR14
• G-protein coupled receptor 14
• UR-2-R
• UR-II-R
• urotensin 2 receptor
• urotensin II receptor
• urotensin-2 receptor
• Urotensin-II R
• UrotensinIIR
• Urotensin-IIR
• UTR
• UTR2
• UTS2R

Background

Urotensin-II R (UR2R) belongs to the G protein-coupled receptor 1 family. UR2R is a high affinity receptor for urotensin-2 and urotensin-2B. The activity of UR2R is mediated by a G protein that activates a phosphatidylinositol-calcium second messenger system. It is most abundantly expressed in the heart and pancreas. Human UR2R has been correlated with cortico-adrenal carcinoma proliferation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Urotensin-II R/GPR14 Antibody (FAB9245G)(2)

Publications using FAB9245G

• Pedard, M;Prevost, L;Carpena, C;Holleran, B;Desrues, L;Dubois, M;Nicola, C;Gruel, R;Godefroy, D;Deffieux, T;Tanter, M;Ali, C;Leduc, R;Prézeau, L;Gandolfo, P;Morin, F;Wurtz, O;Bonnard, T;Vivien, D;Castel, H; The urotensin II receptor triggers an early meningeal response and a delayed macrophage-dependent vasospasm after subarachnoid hemorrhage in male mice Nature communications 2024-09-29 [PMID: 39341842] (Flow Cytometry, Transgenic Mouse)
• Bo Gao, Bo Jiang, Wenhui Xing, Zaiqi Xie, Zhuojing Luo, Weiguo Zou Discovery and Application of Postnatal Nucleus Pulposus Progenitors Essential for Intervertebral Disc Homeostasis and Degeneration Advanced Science 2022-05-01 [PMID: 35195356]