| Applications | IHC |
| Clone | 610712 |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | Alexa Fluor 594 |
| Immunogen | Chinese hamster ovary cell line CHO-derived recombinant human SALM2 Gln32-Gly534 (predicted) Accession # Q9P244 |
| Specificity | Detects human SALM2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human SALM1, 3, or 4 is observed. |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Host | Mouse |
| Purity Statement | Protein A or G purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Storage | Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied |
| Buffer | Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide |
SALM2 (synaptic adhesion-like molecule 2), also called LRFN1 (leucine-rich repeat and fibronectin type-III domain-containing protein 1) is a 105 kDa member of the LRFN family of type I transmembrane glycoproteins. The 740 amino acid (aa) mature human SALM2 contains a 505 aa extracellular domain that includes seven leucine-rich repeats (LRR), an IgC2-like domain, and a fibronectin type-III domain. Mature human SALM2 shares 99% aa identity with mouse and rat SALM2. SALM2 co-localizes with both pre- and post-synaptic proteins at excitatory synapses in mature neurons and promotes neurite outgrowth.
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