Recombinant Human Pin1, HRP-conjugated Protein

• Reactivity: Hu

Recombinant Human Pin1, HRP-conjugated Protein Summary

• Additional Information: Phospho-binding domain
• Accession #: S68520
• Protein/Peptide Type: Recombinant Proteins
• Gene: PIN1

Applications/Dilutions

Publications

Read Publication using HRP2294 in the following applications: Binding Assay 1 publication

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.
• Buffer: Supplied as a 0.2 μM filtered solution in phosphate-buffered saline (PBS) with stabilizers and preservatives.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Recombinant Human Pin1, HRP-conjugated Protein

• dod
• EC 5.2.1.8
• peptidylprolyl cis/trans isomerase, NIMA-interacting 1
• peptidyl-prolyl cis/trans isomerase, NIMA-interacting
• peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
• Peptidyl-prolyl cis-trans isomerase Pin1
• Pin1
• PPIase Pin1
• prolyl isomerase
• protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1
• protein (peptidylprolyl cis/trans isomerase) NIMA-interacting 1
• Rotamase Pin1
• UBL5

Background

Pin1 is a peptidyl-prolyl isomerase (PPI) that targets phosphorylated serine or threonine residues followed by a proline (S/T-P). Isomerization of phosphorylated serine or threonine residues may alter protein confirmation and, subsequently, modify activity. Pin1 is overexpressed in many human breast cancers and has been shown to modify numerous proteins, including p53, NF-kB, c-Jun, cyclin D1, and beta-catenin.

Publications for Pin1 (HRP2294)(1)

Publication using HRP2294

• Mercedes-Camacho AY, Etzkorn FA Enzyme-linked enzyme-binding assay for Pin1 WW domain ligands. Anal. Biochem., 2010-03-15;402(1):77-82. 2010-03-15 [PMID: 20230769] (Binding Assay, Human)

Bioinformatics

• Gene Symbol: PIN1
• Uniprot:
  • S68520()