Polypeptide GalNac Transferase 10/GALNT10 Antibody [DyLight 488]

• Reactivity: Hu, Mu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: DyLight 488

Polypeptide GalNac Transferase 10/GALNT10 Antibody [DyLight 488] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Polypeptide GalNac Transferase 10/GALNT10
  Leu71-Asn603
  Accession # Q86SR1
• Specificity: Detects human and mouse Polypeptide GalNac Transferase 10/GALNT10 in Western blots. In direct ELISA, less than 1% cross-reactivity with recombinant human (rh) GALNT1 and rhGALNT4 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: GALNT10
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Polypeptide GalNac Transferase 10/GALNT10 Antibody [DyLight 488]

• DKFZp586H0623
• EC 2.4.1.41
• FLJ00205
• FLJ11715
• GalNAc transferase 10
• GALNACT10
• GalNAc-T10
• GALNT10
• Polypeptide GalNAc transferase 10
• polypeptide N-acetylgalactosaminyltransferase 10
• PPGALNACT10
• pp-GaNTase 10
• PPGANTASE10
• Protein-UDP acetylgalactosaminyltransferase 10
• UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 10
• UDP-N-acetyl-alpha-D-galactosamine:polypeptideN-acetylgalactosaminyltransferase 10 (GalNAc-T10)

Background

The GALNT10 gene codes for a member of the GalNAc polypeptide N-acetylgalactosaminyltransferases. The enzyme catalyzes the initial reaction in O-linked (mucin-type) oligosaccharide biosynthesis. It creates four isoforms: isoform 1: 603 AA long, nearly 69 kDA; isoform 2: 541 AA long; nearly 62 kDA; isoform 3: 366 AA long; 41 kDA; and isoform 4: 276 AA long: approximately 31 kDA. The GALNT10 gene has been studied with its contribution to thyroiditis. It interacts with genes MUC7, MUC1, GALNT1, GALNT12, and PTCH1 in the metabolism of proteins, mucin type O-glycan biosynthesis, and in post-translational protein modification.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GALNT10