PI 4 Kinase type 2 beta Antibody

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Western Blot: PI 4 Kinase type 2 beta Antibody [NBP1-74233] - Titration: 1.0 ug/ml Positive Control: Mouse Liver.

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

PI 4 Kinase type 2 beta Antibody Summary

Immunogen
Synthetic peptides corresponding to the N terminal of Pi4k2b. Immunizing peptide sequence EDPEFADIVLKAEQAIEIGVFPERISQGSSGSYFVKDSKRNIIGVFKPKS.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PI4K2B
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
Application Notes
This is a rabbit polyclonal antibody against Pi4k2b and was validated on Western blot.
Theoretical MW
52 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 2% Sucrose
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for PI 4 Kinase type 2 beta Antibody

  • EC 2.7.1.67
  • FLJ11105
  • phosphatidylinositol 4-kinase type 2 beta
  • phosphatidylinositol 4-kinase type 2-beta
  • Phosphatidylinositol 4-kinase type II-beta
  • phosphatidylinositol 4-kinase type-II beta
  • PI4KIIB
  • PI4KII-BETA
  • PIK42B

Background

Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) Pi4k2b contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Pi4k2b contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PI4K2B
Uniprot