PDE7B Antibody

Immunohistochemistry-Paraffin: PDE7B Antibody [NB110-55515] - Analysis of anti-PDE7B antibody with human pancreas at concentration 5 ug/ml.

Product Discontinued

PDE7B Antibody Summary

• Immunogen: Synthetic 19 amino acid peptide from C-terminus of human PDE7B.
• Epitope: C-terminal region of human
• Specificity: Human PDE7B. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Primate (95%), Monkey (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PDE7B
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5 ug/ml
• Control:

  PDE7B Overexpression Lysate

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (95%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 0.34 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for PDE7B Antibody

• bA472E5.1
• cAMP-specific 3'-5'-cyclic phosphodiesterase 7B
• EC 3.1.4
• EC 3.1.4.17
• high-affinity cAMP-specific 3'-5'-cyclic phosphodiesterase
• MGC88256
• PDE7B
• phosphodiesterase 7B
• rolipram-insensitive phosphodiesterase type 7

Background

PDE7B is a cAMP specific phosphodiesterase. The cAMP-specific phosphodiesterase type-7 (PDE7) family is comprised of 2 genes (PDE7A and PDE7B) each with multiple splice variants generated by RNA splicing and use of alternate initiation sites. PDE7B has three splice variants (PDE7B1 = 446 amino acid; PDE7B2 =359 amino acids and PDE7B3 = 459 amino acids. Both PDE7B2 ad PDE7B3 posses unique N-terminal sequences. PDE7B is expressed in various tissues including skeletal muscle, heart, lung and testis. PDE7B may be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PDE7B
• Entrez:
  • 27115(Human)