PDE7B Antibody

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Immunohistochemistry-Paraffin: PDE7B Antibody [NB110-40454] - Analysis of anti-PDE7B antibody with human pancreas at concentration 10 ug/ml.

Product Details

Summary
Reactivity Hu, MkSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

PDE7B Antibody Summary

Immunogen
Synthetic 17 amino acid peptide from near N-terminus of human PDE7B.
Specificity
Human PDE7B. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Monkey (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PDE7B
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 10 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (94%), Gorilla (88%), Mouse (88%), Rat (88%), Elephant (88%), Equine (88%), Rabbit (88%), Opossum (82%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PDE7B Antibody

  • bA472E5.1
  • cAMP-specific 3'-5'-cyclic phosphodiesterase 7B
  • EC 3.1.4
  • EC 3.1.4.17
  • high-affinity cAMP-specific 3'-5'-cyclic phosphodiesterase
  • MGC88256
  • phosphodiesterase 7B
  • rolipram-insensitive phosphodiesterase type 7

Background

PDE7B is a cAMP specific phosphodiesterase. The cAMP-specific phosphodiesterase type-7 (PDE7) family is comprised of 2 genes (PDE7A and PDE7B) each with multiple splice variants generated by RNA splicing and use of alternate initiation sites. PDE7B has three splice variants (PDE7B1 = 446 amino acid; PDE7B2 =359 amino acids and PDE7B3 = 459 amino acids. Both PDE7B2 ad PDE7B3 posses unique N-terminal sequences. PDE7B is expressed in various tissues including skeletal muscle, heart, lung and testis. PDE7B may be involved in the control of cAMP-mediated neural activity and cAMP metabolism in the brain.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PDE7B
Entrez
Uniprot