P2X2/P2RX2 Antibody

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Immunohistochemistry: P2X2/P2RX2 Antibody [NB100-1652] - P2X2/P2RX2 is expressed in brain, spinal cord, sensory and autonomic ganglia as well as in neuroendocrine cells

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Guinea Pig
Conjugate
Unconjugated

Order Details

P2X2/P2RX2 Antibody Summary

Immunogen
Synthetic peptide: DSTSTDPKGLAQL, corresponding to amino acids 460-472 of Rat P2X2.
Localization
Plasma membrane
Specificity
P2X2
Isotype
IgG
Clonality
Polyclonal
Host
Guinea Pig
Gene
P2RX2
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Positive Control
P2X2/P2RX2 Lysate (NBL1-14029)

Reactivity Notes

Expected to cross-react with Mouse (100% identity with immunogen) and Guinea pig (100% identity with immunogen) due to sequence homology. Not yet tested in other species.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
0.05% Sodium Azide
Purity
Unpurified

Alternate Names for P2X2/P2RX2 Antibody

  • ATP receptor
  • MGC129601
  • P2RX2
  • P2X purinoceptor 2
  • P2X2
  • P2X2P2X Receptor, subunit 2
  • purinergic receptor P2X, ligand-gated ion channel, 2
  • Purinergic receptor

Background

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. P2X2 has two putative transmembrane domains with intracellular N and C-termini. It can form homomeric channels and heteromeric channels with other members of the family. Six transcript variants encoding six distinct isoforms have been identified for this gene. P2X2 is expressed in brain, spinal cord, sensory and autonomic ganglia as well as in neuroendocrine cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for P2X2/P2RX2 Antibody (NB100-1652)

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Bioinformatics

Gene Symbol P2RX2
Entrez