MCHR1 Antibody (1032149) [Alexa Fluor® 405]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: 1032149
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 405

MCHR1 Antibody (1032149) [Alexa Fluor® 405] Summary

• Immunogen: E. coli-derived human MCHR1
  Met1-Pro113
  Accession # Q99705
• Specificity: Detects human MCHR1 in direct ELISAs. Detects human, mouse, and rat MCHR1 in Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MCHR1 Antibody (1032149) [Alexa Fluor® 405]

• G protein-coupled receptor 24
• GPR24
• GPR24SLC-1
• G-protein coupled receptor 24
• MCH receptor 1
• MCH1R
• MCH-1R
• MCH1RMCHR-1
• MCHR1
• MCH-R1
• melanin-concentrating hormone receptor 1
• MGC32129
• SLC1
• SLC1MCHR
• Somatostatin receptor-like protein

Background

MCHR1 (Melanin-concentrating Hormone Receptor-1), also called GPR24 (G-protein Coupled Receptor 24) or SLC1 (Somatostatin Receptor-like 1), is an approximately 44 kDa, seven-transmembrane receptor for MHC. It is most highly expressed in the brain but is also present in peripheral tissues. Engagement of MHCR1 has effects on food intake, energy homeostasis, anxiety and depression, such that rodents treated with small molecule antagonists weigh less and show reduced anxiety and depression in model systems than untreated rodents. Human MCHR1 shares 74% amino acid (aa) sequence identity with mouse MCHR1 between aa 1-113, and 82% with rat MCHR1 between aa 71-113.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.