HBsAg Antibody (HB3)

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Product Details

Summary
Reactivity ViSpecies Glossary
Applications ELISA, ICC/IF
Clone
HB3
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1 mg/ml

HBsAg Antibody (HB3) Summary

Immunogen
Purified HBsAg from human plasma.
Specificity
The antibody HB3 recognizes following Hepatitis B virus (HBV) subtypes: ayw2, ayw3, ayw4, ayr, adw2, adw4, adrq+, adrq-. Hepatitis B surface antigen (HBsAg) is a marker of infectivity. Specificity of the antibody HB3 was verified by ELISA on panel of virus subtypes identified on International Workshop on HBsAg Subtypes (Paris, April 1975). The antibody HB3 does not cross-block with the antibody HB5.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
S
Purity
Ion exchange chromatography
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:2000
  • Immunocytochemistry/Immunofluorescence 1:10-1:2000

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
15mM Sodium Azide
Concentration
1 mg/ml
Purity
Ion exchange chromatography

Alternate Names for HBsAg Antibody (HB3)

  • HBsAg
  • HBV major surface antigen
  • HBV surface antigen
  • Hepatitis B Virus major surface antigen
  • Hepatitis B Virus Surface Antigen
  • Major surface antigen
  • protein S

Background

Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for HBsAg Antibody (NB500-474) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NB500-474AF405
Alexa Fluor 488 Labeled NB500-474AF488
Alexa Fluor 647 Labeled NB500-474AF647
Alexa Fluor 700 Labeled NB500-474AF700
DyLight 350 Labeled NB500-474UV
DyLight 405 Labeled NB500-474V
DyLight 488 Labeled NB500-474G
DyLight 680 Labeled NB500-474FR
DyLight 755 Labeled NB500-474IR

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Bioinformatics Tool for HBsAg Antibody (NB500-474)

Discover related pathways, diseases and genes to HBsAg Antibody (NB500-474). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Bioinformatics

Gene Symbol S