Host: Mouse Monoclonal
Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
|Product By Gene ID
- protein S
- Hepatitis B Virus Surface Antigen
- Major surface antigen
- Hepatitis B Virus major surface antigen
- HBV major surface antigen
- HBV surface antigen
Research Areas for HBsAg
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Bioinformatics Tool for HBsAg
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