CCDC106 Antibody

Images

 
Western Blot: CCDC106 Antibody [NBP1-77381] - Analysis of CCDC106 in human brain tissue lysate with CCDC106 antibody at (A) 0.5 and (B) 1 ug/mL.
Immunocytochemistry/ Immunofluorescence: CCDC106 Antibody [NBP1-77381] - Immunofluorescence of CCDC106 in rat brain tissue with CCDC106 antibody at 20 ug/mL.
Immunohistochemistry: CCDC106 Antibody [NBP1-77381] - CCDC106 in rat brain tissue with CCDC106 antibody at 5 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

CCDC106 Antibody Summary

Immunogen
Antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human CCDC106. The immunogen is located within the last 50 amino acids of CCDC106.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CCDC106
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.5 - 1ug/ml
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/ml
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
Control Peptide
CCDC106 Peptide (NBP1-77381PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for CCDC106 Antibody

  • coiled-coil domain containing 106
  • coiled-coil domain-containing protein 106
  • HSU79303
  • protein predicted by clone 23882
  • ZNF581

Background

The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for CCDC106 Antibody (NBP1-77381) (0)

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Secondary Antibodies

 

Isotype Controls

Additional CCDC106 Products

Bioinformatics Tool for CCDC106 Antibody (NBP1-77381)

Discover related pathways, diseases and genes to CCDC106 Antibody (NBP1-77381). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on CCDC106

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Bioinformatics

Gene Symbol CCDC106
Uniprot