C1qTNF4/CTRP4 Antibody

Images

 
Western Blot: C1qTNF4/CTRP4 Antibody [NBP1-76629] - Rat brain cell lysate with CTRP4 antibody at (A) 1, (B) 2, and (C) 4 ug/ml.
Immunocytochemistry/ Immunofluorescence: C1qTNF4/CTRP4 Antibody [NBP1-76629] - Immunofluorescence of CTRP4 in Rat Brain cells with CTRP4 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: C1qTNF4/CTRP4 Antibody [NBP1-76629] - Rat brain with CTRP4 antibody at 10 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

C1qTNF4/CTRP4 Antibody Summary

Immunogen
Antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human CTRP4. The immunogen is located within amino acids 240 - 290 of CTRP4.
Specificity
These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
C1QTNF4
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
This antibody can be used for the detection of CTRP4 by Western blot at 1 - 2 mg/ml. Rat brain cell lysate can be used as positive control. CTRP4 antibody is human, mouse and rat reactive. These proteins are often highly modified post-translationally and
Control Peptide
C1qTNF4/CTRP4 Peptide (NBP1-76629PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for C1qTNF4/CTRP4 Antibody

  • C1q and tumor necrosis factor related protein 4
  • C1qTNF4
  • complement C1q tumor necrosis factor-related protein 4
  • complement-c1q tumor necrosis factor-related protein 4
  • CTRP4
  • CTRP4ZACRP4
  • ZACRP4

Background

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Multiple isoforms of mouse CTRP4 have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol C1QTNF4
Uniprot