3-OHKYN Antibody (P3UI) [Janelia Fluor® 669]

• Reactivity: Hu, All
• Applications: WB, ELISA, ICC/IF, IHC
• Clone: P3UI
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 669

3-OHKYN Antibody (P3UI) [Janelia Fluor® 669] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: 3-OHKYN modified KLH
• Specificity: This is specific for 3-hydroxykynureinine (3OH-Kyn) modifications on proteins. It is likely to react with 3OH-Kyn modification on lysine, histidine and cysteine residues on proteins. It does not react with enzymes involved in the degradation of tryptopha
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NB100-597. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for 3-OHKYN Antibody (P3UI) [Janelia Fluor® 669]

• 3039Hydroxykynurenine
• 3-hydroxykynuenine modification

Background

3-hydroxykynurenine is a chromophore metabolite of tryptophan, which acts as UV protectant and an antioxidant in vertebrate lens. 3-OHKYN reacts with proteins to induce cross-linking and chromophore adducts.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.