Species: Hu, Mu, Rt, Pm
Applications: WB, Flow, ICC/IF
Host: Rabbit Monoclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Monoclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Description
Mutations in NF2 (neurofibromin 2) are associated with neurofibromatosis type II which is characterized by Schwann cell tumors (schwannomas) which are benign slow-growing tumors that are resistant to chemotherapeutic intervention. NF2 is a membrane/cytoskeletal associated protein that has been classified as a novel type of tumor suppressor due to its function in membrane organization versus a classic tumor suppressor function that regulates cell cycle machinery. Alternate names for NF2 include merlin, moesin-ezrin-radixin-like protein, schwannomin, schwannomerlin, SCH, ACN, and BANF.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
4771 |
| Alternate Names |
- ACN
- BANF
- Merlin
- moesin-ezrin-radixin like
- Moesin-ezrin-radixin-like protein
- moesin-ezrin-radizin-like protein
- neurofibromin 2 (bilateral acoustic neuroma)
- neurofibromin 2 (merlin)
- neurofibromin-2
- NF2
- SCH
- Schwannomerlin
- Schwannomin
|
