Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC
Host: Rabbit Monoclonal
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IP
Host: Rabbit Monoclonal
Species: Hu
Applications: WB, IHC, Mycoplasma
Host: Mouse Monoclonal
Species: Hu
Applications: AC
Description
CD49e is a type I integral membrane glycoprotein, known as alpha5 integrin, VLA-5 alpha chain. It forms noncovalent heterodimer with integrin beta1 (CD29). CD49e contains two disulfide-linked subunits of 135 kDa and 24 kDa, and is mainly expressed on thymocytes, activated lymphocytes, endothelial cells, osteoblasts, melanoma, and some myeloid leukemia cells. CD49e/CD29 complex binds to fibronection and neural adhesion molecule L1. It mediates monocytes migration, involves in the regulation of cells survival and apoptosis, and co-stimulates T cell activation.
Bioinformatics
| Product By Gene ID |
3678 |
| Alternate Names |
- CD49 antigen-like family member E
- CD49e antigen
- CD49e
- Fibronectin receptor subunit alpha
- fibronectin receptor, alpha subunit
- FNRAVLA5A
- Integrin alpha 5
- integrin alpha-5
- Integrin alpha-F
- integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
- ITGA5
- very late activation protein 5, alpha subunit
- VLA-5 alpha
- VLA-5
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