HSP60 Products

Description

This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Two pseudogenes, both located on chromosome 8, have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq]

Bioinformatics

Product By Gene ID	3329
Alternate Names	60 kDa chaperonin Chaperonin 60 cpn60 GROEL heat shock 60kD protein 1 (chaperonin) heat shock 60kDa protein 1 (chaperonin) Heat shock protein 60 heat shock protein 65 HLD4 HSP60 HSP-60 HSP60SPG13 HSP65 HSPD1 HuCHA60 Mitochondrial matrix protein P1,60 kDa heat shock protein, mitochondrial P60 lymphocyte protein short heat shock protein 60 Hsp60s1 spastic paraplegia 13 (autosomal dominant) SPG13

Research Areas for HSP60

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Membrane Trafficking and Chaperones

Related HSP60 Blog Posts

Check out the latest blog posts on HSP60.

TLR4 - A Guardian of Innate Immunity Toll-like receptor 4 (TLR4) belongs to the family of Toll-like receptors (TLR), and plays a main role in pathogen recognition and innate immunity system activation. The TLR family members are highly conserved proteins that all contain a high degree of...    Read more.

Customer Experience using HSP60 Antibody I began using the HSP60 antibody (NB110-57063) in June of 2010 and it worked well. I do not like to buy antibodies that have not been tested in the species for which I will use them, so I picked this antibody because it had already been tested in rat ...    Read more.

Heat Shock Proteins: An Overview Heat Shock Proteins (HSPs) are a ubiquitous group of molecular chaperone proteins that have evolved unique mechanisms, within their host cells, to facilitate survival in hostile environments such as heat, oxidative (hypoxia), pH and cold. Under permis...    Read more.

The Heat is On: Heat Shock Proteins and the Link to Cancer Novus Biologicals offers an extensive antibody catalog targeting heat shock proteins (HSPs). A large protein group covering a number of families, the HSPs are functionally related by their dramatic upregulation in response to stress. Stress triggers m...    Read more.

Read more HSP60 related blogs.