| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| BSA Free | NB100-56148SS | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| Carrier Free | AF6788-SP | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| BSA Free | NB100-56147SS | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| BSA Free | NBP1-76656-0.025mg | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| BSA Free | NBP2-57196-25ul | |||
| Formulation | Catalog # | Availability | Price | |
|---|---|---|---|---|
| BSA Free | NBP1-76656 | |||
| BSA Free | NBP1-76656-0.025mg | |||
![Western Blot: NLRP1/NALP1 Antibody [NBP1-54899] - NCI-H226 cell lysate, concentration 0.2-1 ug/ml.](http://images.novusbio.com/fullsize/NLRP1-NALP1-Antibody-Western-Blot-NBP1-54899-img0004.jpg "Western Blot: NLRP1/NALP1 Antibody [NBP1-54899] - NCI-H226 cell lysate, concentration 0.2-1 ug/ml.")
![Western Blot: NLRP1/NALP1 Antibody [NBP1-54899] Human MCF7 whole cell. Antibody Dilution: 1ug/ml](http://images.novusbio.com/fullsize/antibody/nbp1-54899_rabbit-polyclonal-nlrp1-nalp1-antibody-western-blot-147202383058..jpg)
![Immunohistochemistry: NLRP1/NALP1 Antibody [NB100-56148] - OHT-induced upregulation of Aim2 inflammasome in the retina. NLRP1 antibody labeling (red) in the inner retina; yellow arrows indicate colocalization with RGC neurons (RBPSM+) in the GCL. Image collected and cropped by Citeab from the following publication (Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury. Front Mol Neurosci (2019) licensed under a CC-BY license.](http://images.novusbio.com/fullsize/NLRP1-NALP1-Antibody-Immunohistochemistry-NB100-56148-img0010.jpg "Immunohistochemistry: NLRP1/NALP1 Antibody [NB100-56148] - OHT-induced upregulation of Aim2 inflammasome in the retina. NLRP1 antibody labeling (red) in the inner retina; yellow arrows indicate colocalization with RGC neurons (RBPSM+) in the GCL. Image collected and cropped by Citeab from the following publication (Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury. Front Mol Neurosci (2019) licensed under a CC-BY license.")
![Western Blot: NLRP1/NALP1 Antibody [NB100-56148] - Analysis of NLRP1/NALP1 in adult human tissue lysates using NLRP1 antibody at 1:2000. Full-length NLRP1 protein was detected at highest levels in kidney, brain and epidermis. A smaller band was detected in thymus, possibly representing a NLRP1/NALP1 breakdown product or alternatively spliced form. 293T/NALP1: positive control, 293T cells transiently transfected with full-length NLRP1.](http://images.novusbio.com/fullsize/NLRP1-NALP1-Antibody-Western-Blot-NB100-56148-img0007.jpg)
![Immunohistochemistry: NLRP1/NALP1 Antibody [NB100-56148] - The NLRP1and NLRP3 proteins localized to distinct cell types in the GCL of naive and NT control retinas: NLRP3 (green) is only expressed in blood vessels (white arrowheads). Twenty four hours after OHT, NLRP3 colocalizes with NLRP1 in RGCs (yellow arrows) and to RBPMS- cells (white arrows). Blue arrowheads denote labeling in RGC axons and dendrites. Bar, 25 um on all panels. Image collected and cropped by Citeab from the following publication (Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury. Front Mol Neurosci (2019) licensed under a CC-BY license.](http://images.novusbio.com/fullsize/NLRP1-NALP1-Antibody-Immunohistochemistry-NB100-56148-img0011.jpg)
![Immunohistochemistry-Paraffin: NLRP1/NALP1 Antibody [NB100-56148] - FFPE normal human tissue sections stained for NALP1 (CARD7/NAC) using NB100-56148 at 1:2000. (A) epidermis, (B) esophagus (C) uterine cervix, and (D) thymus. Hematoxylin-eosin counterstain. In A-C, NALP1 expression is associated with differentiation in stratified epithelial of the skin, esophagus, and cervix.](http://images.novusbio.com/fullsize/NLRP1-NALP1-Antibody-Immunohistochemistry-Paraffin-NB100-56148-img0005.jpg)
![Immunohistochemistry-Paraffin: NLRP1/NALP1 Antibody [NB100-56148] - FFPE human tissue sections stained for NALP1 (CARD7/NAC) using NB100-56148 at 1:2000. (A) bone marrow and (C) brain glioma core from a brain cancer microarray. (B) and (D) are higher magnifications of (A) and (C) respectively. Hemaxotylin-eosin counterstain.](http://images.novusbio.com/fullsize/NLRP1-NALP1-Antibody-Immunohistochemistry-Paraffin-NB100-56148-img0006.jpg)
![Immunocytochemistry/ Immunofluorescence: NLRP1/NALP1 Antibody [NB100-56148] - Gene expression & cellular distribution of NLRP1, NLRP3 & Aim2 sensors in the retina. (A) RNAscope analysis of NLRP1 (green dots, yellow arrows) & NLRP3 (white dots, white arrows) transcript abundance in normotensive control (NT control) & experimental (OHT) retinas at 12 h postinjury. (B) Aim2 transcript (red dots) abundance in normotensive control & experimental retinas. Co-staining for the Muller glia marker glutamine synthetase (GlSyn, green) is added to indicate cellular expression of Aim2 in the GCL layer (yellow arrows) & INL (white arrows) in control & 12 h post-OHT retinas. Bar, 25 μm on all panels. Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/30930743), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nb100-56148_rabbit-polyclonal-nlrp1-nalp1-antibody-31020241534381.jpg)
![Immunocytochemistry/ Immunofluorescence: NLRP1/NALP1 Antibody [NB100-56148] - OHT-induced upregulation of Aim2 inflammasome in the retina. (A) NLRP1 antibody labeling (red) in the inner retina; yellow arrows indicate colocalization with RGC neurons (RBPSM+) in the GCL. (B) Immunohistochemistry for Aim2 protein (red) & Muller glia marker (GlSyn, green). Arrows show colocalization with Muller glia; no colocalization is detected with astrocytes (GFAP, white) in both control & 24 h post-OHT retinas. (C) NLRP3 labeling (green) in the inner retina of naïve & control eyes localized only to blood capillaries (white arrowhead) & astrocytes (yellow arrows), but not to RGCs (RBPMS cells). At 24 h post-injury the labeling in large cells in the GCL & INL (white arrows) are observed. (D) The NLRP1and NLRP3 proteins localized to distinct cell types in the GCL of naïve & NT control retinas: NLRP3 (green) is only expressed in blood vessels (white arrowheads). Twenty four hours after OHT, NLRP3 colocalizes with NLRP1 in RGCs (yellow arrows) & to RBPMS- cells (white arrows). Blue arrowheads denote labeling in RGC axons & dendrites. Bar, 25 μm on all panels. Image collected & cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/30930743), licensed under a CC-BY license. Not internally tested by Novus Biologicals.](http://images.novusbio.com/fullsize/nb100-56148_rabbit-polyclonal-nlrp1-nalp1-antibody-310202415541962.jpg)
![Immunohistochemistry-Paraffin: NLRP1/NALP1 Antibody [NB100-56147] - FFPE normal human bone marrow stained for NALP1 (CARD7/NAP) using NB100-56147 at 1:2000. Hematoxylin-eosin counterstain. Staining is seen in differentiated granulocytes.](http://images.novusbio.com/fullsize/NLRP1-NALP1-Antibody-Immunohistochemistry-Paraffin-NB100-56147-img0003.jpg "Immunohistochemistry-Paraffin: NLRP1/NALP1 Antibody [NB100-56147] - FFPE normal human bone marrow stained for NALP1 (CARD7/NAP) using NB100-56147 at 1:2000. Hematoxylin-eosin counterstain. Staining is seen in differentiated granulocytes.")
![<b>Independent Antibodies Validation. </b>Immunoprecipitation: NLRP1/NALP1 Antibody [NB100-56147] - Analysis of NLRP1/NALP1(NAC/CARD7) in Jurkat cells using NB100-56148 and NB100-56147 NALP1 antibodies. Cell lysates were immunoprecipitated with NB100-56148 (2 uL/million cells) and Western blotted with NB100-56147 at 1:2000.](http://images.novusbio.com/fullsize/NLRP1-NALP1-Antibody-Immunoprecipitation-NB100-56147-img0004.jpg)
![Western Blot: NLRP1/NALP1 Antibody [NBP1-76656] - U937 cell lysate with NALP1 antibody at (A) 1, (B) 2 and (C) 4 ug/ml.](http://images.novusbio.com/fullsize/NLRP1-NALP1-Antibody-Western-Blot-NBP1-76656-img0001.jpg "Western Blot: NLRP1/NALP1 Antibody [NBP1-76656] - U937 cell lysate with NALP1 antibody at (A) 1, (B) 2 and (C) 4 ug/ml.")
![Immunocytochemistry/ Immunofluorescence: NLRP1/NALP1 Antibody - BSA Free [NBP1-76656] - Immunofluorescence of NLRP1/NALP1 in K562 cells with NLRP1/NALP1 antibody at 20 ug/mL.](http://images.novusbio.com/fullsize/nbp1-76656_rabbit-polyclonal-nlrp1-nalp1-antibody-2711202420432310.jpg)
![Immunocytochemistry/ Immunofluorescence: NLRP1/NALP1 Antibody - BSA Free [NBP1-76656] - Immunocytochemistry of NLRP1/NALP1 in K562 cells with NLRP1/NALP1 antibody at 10 ug/mL.](http://images.novusbio.com/fullsize/nbp1-76656_rabbit-polyclonal-nlrp1-nalp1-antibody-2711202420141950.jpg)
![Immunocytochemistry/Immunofluorescence: NLRP1/NALP1 Antibody [NBP2-57196] - Staining of human cell line BJ shows localization to nucleoplasm & cytosol.](http://images.novusbio.com/fullsize/NLRP1-NALP1-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-57196-img0001.jpg "Immunocytochemistry/Immunofluorescence: NLRP1/NALP1 Antibody [NBP2-57196] - Staining of human cell line BJ shows localization to nucleoplasm & cytosol.")
![Western Blot: NALP1 Overexpression Lysate (Adult Normal) [NBL1-13671] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NALP1.](http://images.novusbio.com/fullsize/NALP1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-13671-img0002.jpg "Western Blot: NALP1 Overexpression Lysate (Adult Normal) [NBL1-13671] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NALP1.")