XPB Products

Antibodies
XPB Antibody
XPB Antibody
AF6349
Species: Hu, Mu, Rt
Applications: WB
Host: Goat Polyclonal
XPB Antibody
XPB Antibody
NB100-61059
Species: Hu
Applications: ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
XPB Antibody
XPB Antibody
NB100-61060
Species: Hu, Mu
Applications: WB, ChIP, IP, ICC/IF (-)
Host: Rabbit Polyclonal
Lysates
XPB Overexpression Lysate (Na ...
XPB Overexpression Lysate (Native)
NBL1-10321
Applications: WB
Proteins
Recombinant Human XPB Protein ...
Recombinant Human XPB Protein
H00002071-P01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human XPB Protein ...
Recombinant Human XPB Protein
H00002071-Q01
Species: Hu
Applications: WB, ELISA, PA
XPB Recombinant Protein Antig ...
XPB Recombinant Protein Antigen
NBP2-58758PEP
Species: Hu
Applications: AC
RNAi
XPB RNAi
XPB RNAi
H00002071-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

ERCC3 is a component of the core TFIIH basal transcription factor and functions as an ATP-dependent 3'-5' DNA helicase. ERCC3 is involved in nucleotide excision repair and is the cause of xeroderma pigmentosum complementation group B (XPB), also known as xeroderma pigmentosum II (XP2). Additionally, it has been found to be the cuase of Cockayne syndrome, and trichothiodystrophy (TTD). XPB is an autosomal recessive disease characterized by skin photosensitivity and a predisposition to skin cancer, and neurological abnormalities. Cockayne syndrome and TTD are similarly characterized by photosensitivity and neural abnormalities.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Product By Gene ID 2071
Alternate Names
  • DNA excision repair protein ERCC-3
  • EC 3.6.1
  • BTF2 p89
  • XPBC
  • Xeroderma pigmentosum group B-complementing protein
  • EC 3.6.4.12
  • Basic transcription factor 2 89 kDa subunit
  • xeroderma pigmentosum, complementation group B
  • TFIIH
  • TFIIH basal transcription factor complex helicase XPB subunit
  • RAD25
  • TFIIH p89
  • GTF2H
  • TFIIH basal transcription factor complex 89 kDa subunit
  • BTF2
  • XPBTFIIH 89 kDa subunit
  • DNA repair protein complementing XP-B cells
  • excision repair cross-complementing rodent repair deficiency, complementationgroup 3 (xeroderma pigmentosum group B complementing)

Research Areas for XPB

Find related products by research area and learn more about each of the different research areas below.

Cancer
DNA Repair
Nucleotide Excision Repair

PTMs for XPB

Learn more about PTMs related to XPB.

Phosphorylation
Cleavage
Oxidation
Methylation

Bioinformatics Tool for XPB

Discover related pathways, diseases and genes to XPB. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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