UCP2 Products

Antibodies
UCP2 Antibody [Unconjugated]
UCP2 Antibody [Unconjugated]
AF4739
Species: Hu, Mu
Applications: WB, Simple Western
Host: Goat Polyclonal
UCP2 Antibody
UCP2 Antibody
H00007351-B01P
Species: Hu, Rt
Applications: WB
Host: Mouse Polyclonal
Lysates
UCP2 Overexpression Lysate (D ...
UCP2 Overexpression Lysate (Denatu...
H00007351-T01
Species: Hu
Applications: WB
UCP2 Overexpression Lysate (N ...
UCP2 Overexpression Lysate (Native)
NBL1-17582
Applications: WB
Proteins
Recombinant Human UCP2 Protei ...
Recombinant Human UCP2 Protein
H00007351-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
UCP2 RNAi
UCP2 RNAi
H00007351-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 7351
Alternate Names
  • UCPH
  • mitochondrial uncoupling protein 2
  • Solute carrier family 25 member 8
  • SLC25A8BMIQ4
  • UCP 2
  • uncoupling protein 2 (mitochondrial, proton carrier)

Bioinformatics Tool for UCP2

Discover related pathways, diseases and genes to UCP2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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