UCP1 Products

Description

Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.

Bioinformatics

Entrez	7350 Human
Uniprot	NP_006349 Human NP_068605 Human NP_068605.1 Human P25874 Human
Product By Gene ID	7350
Alternate Names	SLC25A7mitochondrial brown fat uncoupling protein 1 Solute carrier family 25 member 7 thermogenin Thermogenin UCP 1 UCP uncoupling protein 1 (mitochondrial, proton carrier)