Species: Hu, Mu, Bv, Ca
Applications: WB, ELISA, IHC
Host: Goat Polyclonal
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IP, MA
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ELISA, ICC/IF, KD
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron (Kwon et al., 2003 [PubMed 14585983]).[supplied by OMIM]
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
23304 |
| Alternate Names |
- bA49A4.1
- C6orf133MGC71112
- chromosome 6 open reading frame 133
- dJ242G1.1
- dJ392M17.3
- DKFZp686C08114
- E3 ubiquitin-protein ligase UBR2
- EC 6.3.2.-
- KIAA0349FLJ36357
- N-recognin-2
- RP3-392M17.3
- ubiquitin protein ligase E3 component n-recognin 2
- Ubiquitin-protein ligase E3-alpha-2
- Ubiquitin-protein ligase E3-alpha-II
|
