TRPM4 Products

Description

TRPM4 and its close homologue TRPM5 are the only two members of the large TRP superfamily of cation channels that are impermeable to Ca(2+). TRPM4, undergoes a fast desensitization to Ca(2+). The Ca(2+) sensitivity of TRPM4 is regulated by ATP, PKC-dependent phosphorylation, and calmodulin binding at the Cterminus. TRPM4-mediated depolarization modulates Ca2+ oscillations, with downstream effects on cytokine production in T lymphocytes.

Bioinformatics

Product By Gene ID	54795
Alternate Names	Calcium-activated non-selective cation channel 1 FLJ20041 hTRPM4 Long transient receptor potential channel 4 LTrpC4 LTrpC-4 Melastatin-4 PFHB1B transient receptor potential cation channel subfamily M member 4 transient receptor potential cation channel, subfamily M, member 4 TRPM4 TRPM4B

Research Areas for TRPM4

Find related products by research area and learn more about each of the different research areas below.

Neuroscience
Signal Transduction

Related TRPM4 Blog Posts

Check out the latest blog posts on TRPM4.

Winter is coming, and TRPM8 welcomes the cold! TRPM8, or transient receptor potential melastatin 8, is a nonselective cation channel that is activated by cold environments and menthol-like cooling compounds.  While TRPM8 is best known for its location in peripheral nerve endings, it has functio...    Read more.

Read more TRPM4 related blogs.