Species: Hu, Mu, Rt, Pm
Applications: WB, Flow, IHC
Host: Rabbit Monoclonal
Species: Mu
Applications: WB
Host: Rat Monoclonal
Species: Hu
Applications: ICC/IF
Host: Rabbit Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMPresponse element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active whendephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 withTAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potentcoactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activationof the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR)
Bioinformatics
| Entrez |
Human
|
| Product By Gene ID |
64784 |
| Alternate Names |
- CREB regulated transcription coactivator 3
- FLJ21868
- TORC-3
- TORC3CREB-regulated transcription coactivator 3
- Transducer of CREB protein 3
- transducer of regulated cAMP response element-binding protein (CREB) 3
- Transducer of regulated cAMP response element-binding protein 3
- transducer of regulated CREB protein 3
|
![Immunocytochemistry TORC3/CRTC3 Antibody (2069D) [Unconjugated]](http://images.novusbio.com/fullsize2/TORC3_MAB9455_Immunocytochemistry__Immunofluorescence_21097.jpg)
