TORC3/CRTC3 Products

Description

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMPresponse element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active whendephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 withTAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potentcoactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activationof the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR)

Bioinformatics

Entrez	64784 Human
Product By Gene ID	64784
Alternate Names	Transducer of regulated cAMP response element-binding protein 3 transducer of regulated CREB protein 3 Transducer of CREB protein 3 transducer of regulated cAMP response element-binding protein (CREB) 3 FLJ21868 TORC3CREB-regulated transcription coactivator 3 TORC-3 CREB regulated transcription coactivator 3

Diseases related to TORC3/CRTC3

Discover more about diseases related to TORC3/CRTC3.

Mucoepidermoid Carcinoma
Leukemia, T-cell
Carcinoma
Neoplasms
Leukemia
Salivary Gland Neoplasms
Neoplasm Metastasis
Salivary Gland Diseases
Salivary Gland Carcinoma
Oncogene Fusion
Autoimmune Diseases
Insulin Resistance
Malignant Neoplasms
Autoimmune Reaction
Obesity
Nervousness
Inflammation
Htlv-i Infections
Lymphoid Leukemia
Chronic Lymphocytic Leukemia

Pathways for TORC3/CRTC3

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Cellular Respiration
Reverse Transcription
Viral Transcription
Fatty Acid Oxidation
Rna Interference

PTMs for TORC3/CRTC3

Learn more about PTMs related to TORC3/CRTC3.

Phosphorylation
Dephosphorylation

Bioinformatics Tool for TORC3/CRTC3

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