TLR5 Products

Antibodies
TLR5 Antibody
TLR5 Antibody
NBP2-24827
Species: Hu, Mu, Rt, Po
Applications: WB, Flow, IHC-P
Host: Rabbit Polyclonal
Lysates
TLR5 Overexpression Lysate (N ...
TLR5 Overexpression Lysate (Native)
NBL1-16954
Applications: WB
Proteins
TLR5 Partial Recombinant Prot ...
TLR5 Partial Recombinant Protein
H00007100-Q01
Species: Hu
Applications: WB, ELISA, PA
TLR5 Recombinant Protein
TLR5 Recombinant Protein
H00007100-Q03
Species: Hu
Applications: WB, ELISA, PA
TLR5 Peptide
TLR5 Peptide
NBP1-76661PEP
Species: Hu
Applications: B/N
RNAi
TLR5 RNAi
TLR5 RNAi
H00007100-R02
Species: Hu
Reporter Cell Lines
Human TLR5 Stable Cell Line
Human TLR5 Stable Cell Line
NBP2-26269
Host: HEK293

Description

The Toll like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin 1 receptor-associated kinase (IRAK) signaling pathway. Toll-like receptor 5 (TLR5) expression is upregulated following exposure to bacteria or to the TLR5 agonist, flagellin. Gram-negative bacteria, stimulate monocyte/macrophage cells in a TLR5-specific, CD14-independent manner. The TLR5 receptor thus appears to be the principal means by which the innate immune system recognizes flagellated bacterial pathogens.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Product By Gene ID 7100
Alternate Names
  • MGC126430
  • SLEB1FLJ10052
  • TIL3Toll/interleukin-1 receptor-like protein 3
  • MGC126431
  • toll-like receptor 5

Research Areas for TLR5

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
Immunology
Innate Immunity
Prostate Cancer
Toll-Like Receptors

Bioinformatics Tool for TLR5

Discover related pathways, diseases and genes to TLR5. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related TLR5 Blog Posts

Check out the latest blog posts on TLR5.
The role of TLR4 in breast cancer
Toll like receptors (TLRs) are highly conserved proteins that are first known for their role in pathogen recognition and immune response activation.  In order to elicit the necessary immune response in reaction to a foreign pathogen, TLRs trigger cy...    Read more.
Read more TLR5 related blogs.