TIMP-1 Products

Description

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.

Bioinformatics

Entrez	7076 Human
Product By Gene ID	7076
Alternate Names	CLGI Collagenase inhibitor collagenase inhibitor) EPATIMP-1 EPO erythroid potentiating activity Erythroid-potentiating activity Fibroblast collagenase inhibitor FLJ90373 HCI metalloproteinase inhibitor 1 TIMP metallopeptidase inhibitor 1 TIMP1 TIMP-1 TIMPtissue inhibitor of metalloproteinase 1 (erythroid potentiating activity Tissue inhibitor of metalloproteinases 1

Research Areas for TIMP-1

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Cell Cycle and Replication
Cellular Markers