TIF1 alpha Products

Description

The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Bioinformatics

Entrez	8805 Human 21848 Mouse
Uniprot	O15164 Human
Product By Gene ID	8805
Alternate Names	E3 ubiquitin-protein ligase TRIM24 EC 6.3.2 EC 6.3.2.- hTIF1 PTC6 RING finger protein 82 RNF82 RNF82Tif1a TIF1 alpha TIF1 TIF1A TIF1-alpha TIF1ATIF1ALPHA TIF1TF1A transcription intermediary factor 1-alpha transcriptional intermediary factor 1 TRIM24 tripartite motif containing 24 tripartite motif-containing 24 Tripartite motif-containing protein 24

Research Areas for TIF1 alpha

Find related products by research area and learn more about each of the different research areas below.

Protein Kinase
Zinc Finger