TEM7/PLXDC1 Products

Antibodies
TEM7/PLXDC1 Antibody
TEM7/PLXDC1 Antibody
NBP1-86954
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
TEM7/PLXDC1 Antibody
TEM7/PLXDC1 Antibody
NBP1-76833
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
TEM7/PLXDC1 Antibody Pair
TEM7/PLXDC1 Antibody Pair
H00057125-PW1
Species: Hu
Applications: WB, IP
Lysates
TEM7/PLXDC1 Overexpression Ly ...
TEM7/PLXDC1 Overexpression Lysate ...
H00057125-T01
Species: Hu
Applications: WB
TEM7/PLXDC1 Overexpression Ly ...
TEM7/PLXDC1 Overexpression Lysate ...
NBL1-14532
Applications: WB
Proteins
TEM7/PLXDC1 Recombinant Prote ...
TEM7/PLXDC1 Recombinant Protein
H00057125-P01
Species: Hu
Applications: WB, ELISA, PA
TEM7/PLXDC1 Partial Recombina ...
TEM7/PLXDC1 Partial Recombinant Pr...
H00057125-Q01
Species: Hu
Applications: WB, ELISA, PA
TEM7/PLXDC1 Recombinant Prote ...
TEM7/PLXDC1 Recombinant Protein An...
NBP1-86954PEP
Species: Hu
Applications: AC
RNAi
TEM7/PLXDC1 RNAi
TEM7/PLXDC1 RNAi
H00057125-R01V
Species: Hu
Applications: WB, RNAi SP
TEM7/PLXDC1 RNAi
TEM7/PLXDC1 RNAi
H00057125-R02
Species: Hu

Description

Recently, using SAGE (Serial Analysis of Gene Expression) technology, St. Croix et al, have identified 46 genes, whose expression is specifically elevated in tumor-associated endothelium. Nine of these genes were prominently expressed only in tumor endothelial cells (EC), but were absent or barely detectable in normal ECs, and named as Tumor Endothelial Markers (TEMs, TEM 1-9). TEM7 (Tumor endothelial marker 7) transcripts are specifically expressed in the endothelium of colorectal cancer, primary cancers of lung, pancreas, breast, and brain. TEM7 is expressed specifically in endothelium of these cancers, whether primary or metastasis. The other six members of this family (TEM1, 3, 4, 5, 8, and 9) also show similar expression pattern in lung and brain tumors, and liver metastasis. Since most of the genes expressed differentially in tumor endothelium are also expressed during angiogenesis, these newly discovered genes might provide important resources for basic and clinical studies of human angiogenesis.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 57125
Alternate Names
  • plexin domain-containing protein 1
  • Tumor endothelial marker 7
  • FLJ45632
  • Tumor endothelial marker 3
  • TEM3FLJ36270
  • TEM7DKFZp686F0937
  • plexin domain containing 1,2410003I07Rik

Pathways for TEM7/PLXDC1

View related products by pathway and learn more about each of the pathways below.

Regeneration
Cell Proliferation
Phagocytosis
Gene Silencing
Angiogenesis
Endothelial Cell Proliferation
Antibody-dependent Cellular Cytotoxicity

Research Areas for TEM7/PLXDC1

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis

Bioinformatics Tool for TEM7/PLXDC1

Discover related pathways, diseases and genes to TEM7/PLXDC1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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