Syndecan-1/CD138 Products

Antibodies
Syndecan-1/CD138 Antibody (B- ...
Syndecan-1/CD138 Antibody (B-A38)
NB100-64980
Species: Hu
Applications: WB, Flow, Func, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Mouse Monoclonal
Syndecan-1/CD138 Antibody
Syndecan-1/CD138 Antibody
AF2780
Species: Hu
Applications: WB, IHC, ELISA(Cap)
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Syndecan-1/CD138 Antibody (1A ...
Syndecan-1/CD138 Antibody (1A3H4)
Species: Hu, Mu
Applications: WB, ELISA, Flow, ICC/IF, IHC
Host: Mouse Monoclonal
ELISA Kits
Syndecan-1/CD138 ELISA Kit [B ...
Syndecan-1/CD138 ELISA Kit [Biotin]
KA3851
Applications: ELISA
Lysates
Syndecan-1/CD138 Overexpressi ...
Syndecan-1/CD138 Overexpression Ly...
NBP2-10760
Applications: WB
Proteins
Syndecan-1/CD138 Recombinant ...
Syndecan-1/CD138 Recombinant Protein
NBP1-99057
Species: Hu
Applications: PAGE
Syndecan-1/CD138 Recombinant ...
Syndecan-1/CD138 Recombinant Protein
H00006382-P01
Species: Hu
Applications: WB, ELISA, PA
Syndecan-1/CD138 Recombinant ...
Syndecan-1/CD138 Recombinant Prote...
NBP1-88135PEP
Species: Hu
Applications: AC

Description

CD138, also known as Syndecan-1, is a transmembrane heparin sulfate proteoglycan that binds type I collagen. The relative molecular mass of CD138 is found to vary between 20-95 kDa due to the presence of a variable number of GAG modifications on each CD138 molecule. This protein appears to mediate binding of cells to the extracellular matrix. Among mature tissues, CD138 is expressed on simple and stratified epithelia, endothelial cells, and fibroblasts. (2,3) While stratified keratinocytes express CD138, their malignant transformation suppresses CD138 expression. Wound repair processes alter patterns of CD138 expression. Among hematopoietic cells, CD138 is expressed by immunoglobulin-negative pre-B cells in the bone marrow, immature B cells and by terminally differentiated plasma cells in lymphoid organs. CD138 expression has not been observed on mature, circulating peripheral B lymphocytes, however. (4-7) CD138 is also strongly expressed by multiple myeloma-derived cell lines and elevated levels of CD138 are present in the serum of patients with multiple myeloma, a negative prognostic indicator for the disease. (8)

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 6382
Alternate Names
  • SDC
  • syndecan-1
  • syndecan
  • syndecan proteoglycan 1
  • CD138
  • SYND1heparan sulfate proteoglycan fibroblast growth factor receptor
  • CD138 antigen
  • syndecan 1

Bioinformatics Tool for Syndecan-1/CD138

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