SREC-I/SCARF1 Products

Description

SCARF1 is recognised by this antibody is a scavenger receptor that is expressed in endothelial cells and mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Transcription factors ZNF444/EZF-2 and SP1 are found to be responsible for the regulation of this gene. Five alternatively spliced transcript variants encoding distinct isoforms have been described.

Bioinformatics

Entrez	8578 Human
Uniprot	Q14162 Human NP_003684 Human
Product By Gene ID	8578
Alternate Names	Scavenger receptor expressed by endothelial cells 1 MGC47738 SREC-I Acetyl LDL receptor SRECscavenger receptor expressed by endothelial cells KIAA0149endothelial cells scavenger receptor SREC1 scavenger receptor class F, member 1

Diseases related to SREC-I/SCARF1

Discover more about diseases related to SREC-I/SCARF1.

Infective Disorder
Infection By Cryptococcus Neoformans
Atherosclerosis
Neoplasms
Candidiasis
Autoimmunity
Cell Invasion
Influenza
Tetanus
Uremia
Hepatitis
Thymoma
Gonorrhea
Tissue Adhesions
Hepatitis C
Pneumonia
Tumor Angiogenesis
Kidney Diseases
Inflammation

Pathways for SREC-I/SCARF1

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Immune Response
Endocytosis
Cell Activation
Adaptive Immune Response
Cytokine Production
T Cell Activation
Glycosylation
Transcytosis
Antimicrobial Peptide Production
Localization
Receptor Internalization
Phagocytosis
Angiogenesis
Pathogenesis

Research Areas for SREC-I/SCARF1

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Lipid and Metabolism

PTMs for SREC-I/SCARF1

Learn more about PTMs related to SREC-I/SCARF1.

Acetylation
Biotinylation
Glycosylation
Ribosylation

Bioinformatics Tool for SREC-I/SCARF1

Discover related pathways, diseases and genes to SREC-I/SCARF1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.