SREC-I/SCARF1 Products

Description

SCARF1 is recognised by this antibody is a scavenger receptor that is expressed in endothelial cells and mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Transcription factors ZNF444/EZF-2 and SP1 are found to be responsible for the regulation of this gene. Five alternatively spliced transcript variants encoding distinct isoforms have been described.

Bioinformatics

Entrez	8578 Human
Uniprot	NP_003684 Human Q14162 Human
Product By Gene ID	8578
Alternate Names	Scavenger receptor expressed by endothelial cells 1 MGC47738 SREC-I Acetyl LDL receptor SRECscavenger receptor expressed by endothelial cells KIAA0149endothelial cells scavenger receptor SREC1 scavenger receptor class F, member 1

Diseases related to SREC-I/SCARF1

Discover more about diseases related to SREC-I/SCARF1.

Infective Disorder
Infection By Cryptococcus Neoformans
Atherosclerosis
Neoplasms
Candidiasis
Autoimmunity
Cell Invasion
Influenza
Tetanus
Uremia
Hepatitis
Thymoma
Gonorrhea
Tissue Adhesions
Hepatitis C
Pneumonia
Tumor Angiogenesis
Kidney Diseases
Inflammation

Pathways for SREC-I/SCARF1

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Immune Response
Endocytosis
Cell Activation
Adaptive Immune Response
Cytokine Production
T Cell Activation
Glycosylation
Transcytosis
Antimicrobial Peptide Production
Localization
Receptor Internalization
Phagocytosis
Angiogenesis
Pathogenesis

Research Areas for SREC-I/SCARF1

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Lipid and Metabolism

PTMs for SREC-I/SCARF1

Learn more about PTMs related to SREC-I/SCARF1.

Acetylation
Biotinylation
Glycosylation
Ribosylation

Bioinformatics Tool for SREC-I/SCARF1

Discover related pathways, diseases and genes to SREC-I/SCARF1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.