Sortilin Products

Antibodies
Sortilin Antibody [Unconjugat ...
Sortilin Antibody [Unconjugated]
AF2934
Species: Mu
Applications: WB, Simple Western, IHC, Block
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Sortilin Antibody [Unconjugat ...
Sortilin Antibody [Unconjugated]
AF3154
Species: Hu
Applications: WB, Simple Western, IHC, Block
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Sortilin Antibody (334708) [U ...
Sortilin Antibody (334708) [Unconj...
MAB3154
Species: Hu, Mu, Rt
Applications: WB, Simple Western
Host: Mouse Monoclonal
Proteins
Sortilin Partial Recombinant ...
Sortilin Partial Recombinant Protein
H00006272-Q01
Species: Hu
Applications: WB, ELISA, PA
Sortilin Recombinant Protein ...
Sortilin Recombinant Protein Antigen
NBP1-89745PEP
Species: Hu
Applications: AC
RNAi
Sortilin RNAi
Sortilin RNAi
H00006272-R01
Species: Hu

Description

Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Rat
Product By Gene ID 6272
Alternate Names
  • Neurotensin receptor 3
  • sortilin
  • Glycoprotein 95
  • Gp95LDLCQ6
  • NT3NTR3
  • 100 kDa NT receptor
  • sortilin 1

Research Areas for Sortilin

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Golgi Apparatus Markers

PTMs for Sortilin

Learn more about PTMs related to Sortilin.

Cleavage

Bioinformatics Tool for Sortilin

Discover related pathways, diseases and genes to Sortilin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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