SETD8 Products

Antibodies
SETD8 Antibody (3G9)
SETD8 Antibody (3G9)
NBP2-45792
Species: Hu
Applications: WB, IHC
Host: Mouse monoclonal
SETD8 Antibody
SETD8 Antibody
NBP2-20320
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
SETD8 Overexpression Lysate ( ...
SETD8 Overexpression Lysate (Native)
NBL1-15870
Applications: WB

Description

Histone methyltransferase that specifically monomethylates 'Lys-20' of histone H4. H4 'Lys-20'monomethylation is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression.Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes.Required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNAduring mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substratecompared to free histones

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 387893
Alternate Names
  • SET8
  • KMT5A
  • PRSET7
  • H4-K20-HMTase SETD8
  • PR/SET07
  • PR/SET domain containing protein 8
  • Lysine N-methyltransferase 5A
  • H4K20-specific histone methyltransferase splice variant Set8b
  • Histone-lysine N-methyltransferase SETD8
  • SET07SET8H4-K20-specific histone methyltransferase
  • PR-Set7EC 2.1.1.43
  • KMT5A SET domain-containing protein 8
  • PR/SET domain-containing protein 07
  • SET domain containing (lysine methyltransferase) 8

Research Areas for SETD8

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Epigenetics

Bioinformatics Tool for SETD8

Discover related pathways, diseases and genes to SETD8. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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