SETD8 Products

SETD8 Overexpression Lysate
SETD8 Overexpression Lysate
Species: Hu
Applications: WB
SETD8 Recombinant Protein Ant ...
SETD8 Recombinant Protein Antigen
Species: Hu
Applications: AC


Histone methyltransferase that specifically monomethylates 'Lys-20' of histone H4. H4 'Lys-20'monomethylation is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression.Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes.Required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNAduring mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substratecompared to free histones


Entrez Human
Uniprot Human
Product By Gene ID 387893
Alternate Names
  • SET8
  • KMT5A
  • PRSET7
  • H4-K20-HMTase SETD8
  • PR/SET07
  • PR/SET domain containing protein 8
  • Lysine N-methyltransferase 5A
  • H4K20-specific histone methyltransferase splice variant Set8b
  • Histone-lysine N-methyltransferase SETD8
  • SET07SET8H4-K20-specific histone methyltransferase
  • PR-Set7EC
  • KMT5A SET domain-containing protein 8
  • PR/SET domain-containing protein 07
  • SET domain containing (lysine methyltransferase) 8

Research Areas for SETD8

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Cell Cycle and Replication

Bioinformatics Tool for SETD8

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