RUVBL1 Products

Antibodies
RUVBL1 Antibody
RUVBL1 Antibody
NBP2-27147
Species: Hu
Applications: WB, IHC-P
Host: Rabbit Polyclonal
RUVBL1 Antibody
RUVBL1 Antibody
NBP1-84914
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
RUVBL1 Antibody (3G4-1F8)
RUVBL1 Antibody (3G4-1F8)
H00008607-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, PLA
Host: Mouse Monoclonal
Lysates
RUVBL1 Overexpression Lysate ...
RUVBL1 Overexpression Lysate (Native)
NBL1-15631
Applications: WB
Proteins
RUVBL1 Recombinant Protein An ...
RUVBL1 Recombinant Protein Antigen
NBP1-84914PEP
Species: Hu
Applications: AC
RUVBL1 Recombinant Protein An ...
RUVBL1 Recombinant Protein Antigen
NBP1-84913PEP
Species: Hu
Applications: AC
RUVBL1 Recombinant Protein
RUVBL1 Recombinant Protein
NBP1-50845
Applications: PAGE
RNAi
RUVBL1 RNAi
RUVBL1 RNAi
H00008607-R01
Species: Hu

Description

Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. RUVBL1 plays an essential role in oncogenic transformation by MYC and also modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 8607
Alternate Names
  • EC 3.6.1
  • EC 3.6.4.12,49 kDa TBP-interacting protein
  • 49 kDa TATA box-binding protein-interacting protein
  • TATA binding protein interacting protein 49 kDa
  • Pontin 52
  • ruvB-like 1
  • Nuclear matrix protein 238
  • PONTIN
  • TIP49a
  • RuvB (E coli homolog)-like 1
  • Rvb1
  • TIH1
  • TIP60-associated protein 54-alpha
  • RVB1
  • NMP 238
  • Pontin52
  • INO80 complex subunit H
  • ECP54
  • INO80HTIP49A
  • TIP49TAP54-alpha
  • NMP238ECP-54
  • 54 kDa erythrocyte cytosolic protein
  • RuvB-like 1 (E. coli)

Research Areas for RUVBL1

Find related products by research area and learn more about each of the different research areas below.

Core ESC-Like Genes
Stem Cell Markers
Wnt Signaling Pathway

PTMs for RUVBL1

Learn more about PTMs related to RUVBL1.

Acetylation
Phosphorylation
Methylation
Sumoylation
Dephosphorylation

Bioinformatics Tool for RUVBL1

Discover related pathways, diseases and genes to RUVBL1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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