Species: Hu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: CyTOF-ready, Flow
Host: Mouse Monoclonal
Species: Hu
Applications: WB, IP, ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Description
Retinoid related orphan receptor alpha (ROR alpha) is a NR1 Thyroid Hormone Like Receptor. To date, ROR alpha, beta, and gamma subtypes have been discovered. ROR alpha has been shown to affect the development of the central nervous system. Deletion of ROR alpha in mice causes severe impairment in the differentiation of cerebellar Purkinje neurons and results in the "staggerer" phenotype. ROR alpha has been suggested as a potential target in the treatment of chronic inflammatory diseases, including atherosclerosis and rheumatoid arthritis.
Bioinformatics
| Entrez |
Human |
| Uniprot |
Human Human Human Human Human Human Human Human |
| Product By Gene ID |
6095 |
| Alternate Names |
- DKFZp686M2414
- MGC119326
- NR1F1MGC119329
- nuclear receptor ROR-alpha
- Nuclear receptor RZR-alpha
- Nuclear receptor subfamily 1 group F member 1
- RAR-related orphan receptor A
- RAR-related orphan receptor alpha
- retinoic acid receptor-related orphan receptor alpha
- retinoid-related orphan receptor alpha
- Retinoid-related orphan receptor-alpha
- ROR1
- ROR2
- ROR3
- RZR-ALPHA
- RZRAROR-alpha
- transcription factor RZR-alpha
|
Research Areas for ROR alpha/NR1F1
Find related products by research area and learn more about each of the different research areas below.
GPCR