Rif1 Products

Description

Rif1 (Rap1-interacting factor homolog) is a protein whose primary function is in the DNA-damage response, RIF1 forms foci that colocalize with other DNA damage response factors, after induction of double-strand breaks. Rif1 localizes to double strand breaks in an ATM (ataxia telangiectasia mutated)- and 53BP1-dependent manner and functions in the intra-S-phase checkpoint that serves to slow down DNA synthesis when DNA damage has occurred.

Bioinformatics

Entrez	295602 Rat 51869 Mouse 55183 Human
Uniprot	NP_060621 Human NP_060621.3 Human Q5UIP0 Human Q6PR54 Mouse
Product By Gene ID	55183
Alternate Names	DKFZp434D1026 DKFZp781N1478 FLJ10599 FLJ12870 RAP1 interacting factor homolog (yeast) Rap1-interacting factor 1 homolog telomere-associated protein RIF1

Related Rif1 Blog Posts

Check out the latest blog posts on Rif1.

The recent relationship of BRCA1 and 53BP1 The p53-binding protein 1 (53BP1) is a DNA damage response factor, which is recruited to nuclear structures at the site of DNA damage.  DNA double-strand breaks (DSBs) are mutations that are detrimental to cell viability and genome stability, and m...    Read more.

Read more Rif1 related blogs.