Species: Hu, Pm
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Species: Hu, Mk, Pm
Applications: ICC/IF, IHC, IHC-P, IP, PLA, WB (-)
Host: Rabbit Polyclonal
Species: Hu, Pm
Applications: WB, IHC, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Rif1 (Rap1-interacting factor homolog) is a protein whose primary function is in the DNA-damage response, RIF1 forms foci that colocalize with other DNA damage response factors, after induction of double-strand breaks. Rif1 localizes to double strand breaks in an ATM (ataxia telangiectasia mutated)- and 53BP1-dependent manner and functions in the intra-S-phase checkpoint that serves to slow down DNA synthesis when DNA damage has occurred.
Bioinformatics
| Entrez |
Human
Mouse
Rat
|
| Uniprot |
Human
Human
Human
Mouse
|
| Product By Gene ID |
55183 |
| Alternate Names |
- telomere-associated protein RIF1
- DKFZp434D1026
- FLJ10599
- Rap1-interacting factor 1 homolog
- FLJ12870
- DKFZp781N1478
- RAP1 interacting factor homolog (yeast)
|
Bioinformatics Tool for Rif1
Discover related pathways, diseases and genes to Rif1. Need help? Read the
Bioinformatics Tool Guide for instructions on using this tool.
Related Rif1 Blog Posts
Check out the latest blog posts on Rif1.
The recent relationship of BRCA1 and 53BP1
The p53-binding protein 1 (53BP1) is a DNA damage response factor, which is recruited to nuclear structures at the site of DNA damage. DNA double-strand breaks (DSBs) are mutations that are detrimental to cell viability and genome stability, and m... Read more.
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Read more Rif1 related blogs.
