PITX2 Products

Antibodies
PITX2 Antibody (2G6)
PITX2 Antibody (2G6)
H00005308-M01
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
PITX2 Antibody
PITX2 Antibody
AF7388
Species: Hu
Applications: IHC
Host: Sheep Polyclonal
PITX2 Antibody
PITX2 Antibody
H00005308-D01P
Species: Hu
Applications: WB, PLA
Host: Rabbit Polyclonal
Lysates
PITX2 Overexpression Lysate ( ...
PITX2 Overexpression Lysate (Native)
NBL1-14448
Applications: WB
PITX2 Overexpression Lysate ( ...
PITX2 Overexpression Lysate (Native)
NBL1-14446
Applications: WB
PITX2 Overexpression Lysate ( ...
PITX2 Overexpression Lysate (Native)
NBL1-14447
Applications: WB
Proteins
PITX2 Recombinant Protein Ant ...
PITX2 Recombinant Protein Antigen
NBP2-55572PEP
Species: Hu
Applications: B/N, Ctrl
PITX2 Recombinant Protein Ant ...
PITX2 Recombinant Protein Antigen
NBP2-57409PEP
Species: Hu
Applications: B/N, Ctrl
Recombinant Human PITX2 Prote ...
Recombinant Human PITX2 Protein
H00005308-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
PITX2 RNAi
PITX2 RNAi
H00005308-R03
Species: Hu
Applications: RNAi, RNAi SP
PITX2 RNAi
PITX2 RNAi
H00005308-R02
Species: Hu
Applications: RNAi, RNAi SP
PITX2 RNAi
PITX2 RNAi
H00005308-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

PITX2 encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Human
Human
Mouse
Product By Gene ID 5308
Alternate Names
  • IHG2
  • RIEG bicoid-related homeobox transcription factor
  • IGDS2
  • Solurshin
  • IDG2
  • solurshin
  • ALL1-responsive protein ARP1
  • rieg bicoid-related homeobox transcription factor 1
  • RIEG
  • pituitary homeobox 2
  • Homeobox protein PITX2
  • pituitary homeo box 2
  • RS
  • all1-responsive gene 1
  • Otlx2
  • PTX2
  • IGDS
  • RGSRIEG1Brx1
  • ARP1MGC20144
  • Paired-like homeodomain transcription factor 2MGC111022
  • IRID2
  • paired-like homeodomain 2

Research Areas for PITX2

Find related products by research area and learn more about each of the different research areas below.

Stem Cell Markers

PTMs for PITX2

Learn more about PTMs related to PITX2.

Methylation
Phosphorylation
Acetylation
Demethylation
Carboxylation
Dephosphorylation

Bioinformatics Tool for PITX2

Discover related pathways, diseases and genes to PITX2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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