Species: Hu, Po, Bv
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Phospholipase C delta 1, also known by its gene name PLCD1, has a 756 amino acid long isoform that is approximately 86 kDa and a 777 amino acid long isoform that is approximately 88 kDa. Phospholipase C delta 1 is a member of the phospholipase C family and plays a critical role in the production of intercellular second messenger molecules. Phospholipase C delta 1 is a tumor suppressor and mutations in PLCD1 may be a cause of hereditary leukonychia. Currently research on Phospholipase C delta 1 is related to several diseases and disorders including nail disorders, squamous cell carcinoma, Huntington's disease, Alzheimer's disease, colon carcinoma, breast cancer, esophagitis and hypertension. Phospholipase C delta 1 has also been shown to interact with CALM1, CALM2, CALM3, TGM2 and KPNB1 in pathways such as IGF1R signaling, PKA signaling, sweet taste signaling and CREB Pathway.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
5333 |
| Alternate Names |
- 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-1
- EC 3.1.4.11
- Phosphoinositide phospholipase C-delta-1
- phospholipase C, delta 1
- Phospholipase C-delta-1
- Phospholipase C-III
- PLC-delta-1
- PLC-III
|
Research Areas for Phospholipase C delta 1
Find related products by research area and learn more about each of the different research areas below.
Lipid and Metabolism
