O-GlcNAcase/OGA/MGEA5 Products

Description

The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM]

Bioinformatics

Entrez	10724 Human 76055 Mouse
Uniprot	NP_036347 Human NP_036347.1 Human O60502 Human
Product By Gene ID	10724
Alternate Names	KIAA0679 HEXC Nuclear cytoplasmic O-GlcNAcase and acetyltransferase hyaluronidase in meningioma Meningioma-expressed antigen 5 bifunctional protein NCOAT OGA O-GlcNAcase NCOAT MEA5FLJ23355 FLJ11229 meningioma expressed antigen 5 (hyaluronidase)

Diseases related to O-GlcNAcase/OGA/MGEA5

Discover more about diseases related to O-GlcNAcase/OGA/MGEA5.

Neoplasms
Malignant Neoplasms
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Sarcoma
Headache
Malignant Neoplasm Of Urinary Bladder
Soft Tissue Neoplasms
Bladder Neoplasm
Carcinoma
Fibrosarcoma
Mammary Neoplasms
Meningioma
Malignant Paraganglionic Neoplasm
Lipoma
Inflammation
Tumor Progression
Neurodegenerative Disorders
Insulin Resistance

Pathways for O-GlcNAcase/OGA/MGEA5

View related products by pathway and learn more about each of the pathways below.

Localization
Methylation
Pathogenesis
Aging
Fertilization
Dna Methylation
Regulation Of Gene Expression
Dosage Compensation
Embryo Development
Reverse Transcription
Cell Growth
Angiogenesis
Interphase

PTMs for O-GlcNAcase/OGA/MGEA5

Learn more about PTMs related to O-GlcNAcase/OGA/MGEA5.

Cleavage
Methylation

Bioinformatics Tool for O-GlcNAcase/OGA/MGEA5

Discover related pathways, diseases and genes to O-GlcNAcase/OGA/MGEA5. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.