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HAF109). For additional reference, recombinant human MKK6 (2 ng) was included. A specific band for MKK6 was detected at approximately 39 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
HAF017). A specific band was detected for MKK6 at approximately 39 kDa (as indicated) in the parental HeLa cell line, but is not detectable in knockout HeLa cell line. GAPDH (Catalog # AF5718) is shown as a loading control. This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
Species: Hu, Mu, Rt Applications: WB, KO Host: Goat Polyclonal
HAF008). For additional reference, recombinant human MKK6 (2 ng) was included. A specific band for MKK6 was detected at approximately 38 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
HAF008). A specific band was detected for MKK6 at approximately 39 kDa (as indicated) in the parental HeLa cell line, but is not detectable in knockout HeLa cell line. GAPDH (Catalog # AF5718) is shown as a loading control. This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
Species: Hu, Mu, Rt Applications: WB, KO Host: Rabbit Polyclonal
Mitogen-acitvated protein kinase kinase 6 (MKK6) belongs to the serine/threonine protein kinase family and the MAPK kinase subfamily (MAP2K, MKK or MEKs). MAPKs require dual phosphorylation on threonine and tyrosine residues, an activation step carried out by MAPK kinase (1-2). MKK6, closely related to MKK3, efficiently phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines and environmental stress but not JNK or ERK (3). MTK1 phosphorylates MKK6 on serine 207 and threonine 211 (4).
![Western Blot MKK6/MEK6 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/MKK6_AF16041_Western_Blot_5129.jpg)
![Western Blot MKK6/MEK6 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/MKK6_AF1604_Western_Blot_5128.jpg)
![Knockout Validated MKK6/MEK6 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/MKK6_AF16041_Knockout_Validated_22986.jpg)
![Knockout Validated MKK6/MEK6 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/MKK6_AF1604_Knockout_Validated_22985.jpg)
