MeCP2 Products

Antibodies
MeCP2 Antibody
MeCP2 Antibody
NB100-56326
Species: Hu, Mu, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
MeCP2 Antibody
MeCP2 Antibody
NB600-1101
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
MeCP2 Antibody (4B6)
MeCP2 Antibody (4B6)
H00004204-M01
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC, IHC-P
Host: Mouse Monoclonal
Lysates
MeCP2 Overexpression Lysate ( ...
MeCP2 Overexpression Lysate (Native)
NBL1-12977
Applications: WB
MeCP2 Overexpression Lysate ( ...
MeCP2 Overexpression Lysate (Denat...
H00004204-T01
Applications: WB
Proteins
MeCP2 Recombinant Protein
MeCP2 Recombinant Protein
H00004204-P01
Species: Hu
Applications: WB, ELISA, PA
MeCP2 Partial Recombinant Pro ...
MeCP2 Partial Recombinant Protein
H00004204-Q01
Species: Hu
Applications: WB, ELISA, PA
MeCP2 Recombinant Protein Ant ...
MeCP2 Recombinant Protein Antigen
NBP1-81027PEP
Species: Hu
Applications: AC
RNAi
MeCP2 RNAi
MeCP2 RNAi
H00004204-R01
Species: Hu

Description

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of some cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 4204
Alternate Names
  • X-linked 16
  • AUTSX3
  • DKFZp686A24160
  • MeCp-2 protein
  • mental retardation, X-linked 79
  • methyl CpG binding protein 2 (Rett syndrome)

Research Areas for MeCP2

Find related products by research area and learn more about each of the different research areas below.

Cancer
Chromatin Research
Neuroscience
Phospho-Specific

Bioinformatics Tool for MeCP2

Discover related pathways, diseases and genes to MeCP2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related MeCP2 Blog Posts

Check out the latest blog posts on MeCP2.
New MECP2 Study Suggests Important Link to GABA
MECP2 antibodies are used in DNA methylation studies as well as research into Rett syndrome, a progressive neurological disorder caused by a mutation in the MECP2 gene. Now, a new study has been published by the laboratory where the Rett Syndrome gene...    Read more.
Read more MeCP2 related blogs.