WB, IHC, IHC-P, PEP-ELISAHost:
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Applications: WB, IP
Applications: WB, ELISA, PA, AP
Applications: WB, ELISA, PA, PAGE, AP
Applications: RNAi, RNAi SP
Gene ID: 64135 DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon (IFNB) and a protein kinase C-activating compound, mezerein (MEZ). Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation.
|Product By Gene ID
- Murabutide down-regulated protein
- Melanoma differentiation-associated protein 5
- EC 126.96.36.199
- Interferon-induced with helicase C domain protein 1
- melanoma differentiation associated protein-5
- Helicase with 2 CARD domains
- interferon-induced helicase C domain-containing protein 1
- Clinically amyopathic dermatomyositis autoantigen 140 kDa
- DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide
- MDA5RNA helicase-DEAD box protein 116
- CADM-140 autoantigen
- interferon induced with helicase C domain 1
Research Areas for MDA5
Find related products by research area and learn more about each of the different research areas below.Cell Cycle and Replication
Bioinformatics Tool for MDA5
Discover related pathways, diseases and genes to MDA5. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.
Related MDA5 Blog Posts
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The innate immune system is responsible for reacting to viral infections through recognition of various viral components. Like toll-like receptor 3 (TLR3), MDA5 recognizes double-stranded (ds) RNA which is a molecular pattern indicative of viral infec... Read more.