MDA5 Products

Antibodies
MDA5 Antibody
MDA5 Antibody
NB110-1244
Species: Hu, Mu, Pm
Applications: WB, IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
MDA5 Antibody
MDA5 Antibody
NBP1-76760
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
MDA5 Antibody (1B6)
MDA5 Antibody (1B6)
NBP1-97526
Species: Hu, Mu
Applications: WB, ELISA
Host: Mouse Monoclonal
Lysates
MDA5 Overexpression Lysate
MDA5 Overexpression Lysate
NBL1-11833
Species: Hu
Applications: WB
Proteins
MDA5 Antibody Blocking Peptid ...
MDA5 Antibody Blocking Peptide
NBP1-76761PEP
Species: Hu
Applications: AC
Recombinant Human MDA5 GST (N ...
Recombinant Human MDA5 GST (N-Term...
H00064135-Q01
Species: Hu
Applications: WB, ELISA, PA, PAGE, AP
Recombinant Human MDA5 GST (N ...
Recombinant Human MDA5 GST (N-Term...
H00064135-P01
Species: Hu
Applications: WB, ELISA, PA, AP

Description

Gene ID: 64135 DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon (IFNB) and a protein kinase C-activating compound, mezerein (MEZ). Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 64135
Alternate Names
  • RH116
  • Murabutide down-regulated protein
  • Helicard
  • Melanoma differentiation-associated protein 5
  • EC 3.6.4.13
  • Interferon-induced with helicase C domain protein 1
  • melanoma differentiation associated protein-5
  • Helicase with 2 CARD domains
  • interferon-induced helicase C domain-containing protein 1
  • Clinically amyopathic dermatomyositis autoantigen 140 kDa
  • helicard
  • IDDM19
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide
  • Hlcd
  • MDA-5MGC133047
  • MDA5RNA helicase-DEAD box protein 116
  • CADM-140 autoantigen
  • interferon induced with helicase C domain 1

Research Areas for MDA5

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

Bioinformatics Tool for MDA5

Discover related pathways, diseases and genes to MDA5. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related MDA5 Blog Posts

Check out the latest blog posts on MDA5.
MDA5 - Part of the RIG-I-like Receptor Family
The innate immune system is responsible for reacting to viral infections through recognition of various viral components. Like toll-like receptor 3 (TLR3), MDA5 recognizes double-stranded (ds) RNA which is a molecular pattern indicative of viral infec...    Read more.
Read more MDA5 related blogs.