LRP-6 Products

Antibodies
LRP-6 Antibody (255302) [Unco ...
LRP-6 Antibody (255302) [Unconjuga...
MAB1505
Species: Hu
Applications: Flow, ICC
Host: Mouse Monoclonal
LRP-6 Antibody
LRP-6 Antibody
AF1505
Species: Hu
Applications: WB, Flow
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
LRP-6 [p Ser1490] Antibody [U ...
LRP-6 [p Ser1490] Antibody [Unconj...
AF6649
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
LRP-6 Overexpression Lysate ( ...
LRP-6 Overexpression Lysate (Native)
NBL1-12672
Applications: WB
Proteins
LRP-6 Recombinant Protein Ant ...
LRP-6 Recombinant Protein Antigen
NBP1-86345PEP
Species: Hu
Applications: AC
RNAi
LRP-6 RNAi
LRP-6 RNAi
H00004040-R02
Species: Hu

Description

Please note, this product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot (see Application Notes below). However no additional claims are made for their ability to recognise native protein in any application. LRP6 is essential for the Wnt/beta catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. It is a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. The interaction with DKK1 blocks LRP6-mediated Wnt/beta catenin signaling via LRP6 removal via Kremen proteins-mediated endocytosis.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Product By Gene ID 4040
Alternate Names
  • low-density lipoprotein receptor-related protein 6
  • FLJ90421
  • FLJ90062
  • ADCAD2
  • LRP-6
  • low density lipoprotein receptor-related protein 6

Research Areas for LRP-6

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Stem Cell Signaling Pathway

Bioinformatics Tool for LRP-6

Discover related pathways, diseases and genes to LRP-6. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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