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Lipin 1 Products

Antibodies
Proteins
Lipin 1 Antibody Blocking Pep ...
Lipin 1 Antibody Blocking Peptide
NB110-57150PEP
Applications: AC
Lipin 1 Antibody Blocking Pep ...
Lipin 1 Antibody Blocking Peptide
NB110-57151PEP
Applications: AC
Recombinant Human Lipin 1 GST ...
Recombinant Human Lipin 1 GST (N-T...
H00023175-Q01
Species: Hu
Applications: WB, ELISA, MA, AP

Description

LPIN1 (Lipin-1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC-225; target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPAR 225. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity. A deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.

Bioinformatics

Product By Gene ID 23175
Alternate Names
  • DKFZp781P1796
  • EC 3.1.3.18
  • EC 3.1.3.4
  • EC 5.4.2.7
  • KIAA0188phosphatidate phosphatase LPIN1
  • Lipin 1
  • lipin-1
  • LPIN1
  • PAP1

Research Areas for Lipin 1

Find related products by research area and learn more about each of the different research areas below.

Cell Biology
Cell Cycle and Replication
Cholesterol Metabolism
Diabetes Research
Lipid and Metabolism
Signal Transduction