Laminin alpha 5 Products

Description

Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined.

Bioinformatics

Entrez	16776 Mouse 3911 Human
Uniprot	O15230 Human Q61001 Mouse
Product By Gene ID	3911
Alternate Names	KIAA0533 KIAA1907 laminin alpha-5 chain laminin subunit alpha-5 laminin, alpha 5 Laminin-10 subunit alpha Laminin-11 subunit alpha Laminin-15 subunit alpha